Keira Knightley claims that she is not anorexic, but she explains that her grandmother and great-grandmother suffered from the eating disorder. So she knows it is a dangerous disease.
The clause "So she knows it is a dangerous disease" is a fragment. It is a subordinate clause that does not express a complete thought and cannot stand on its own.
"So" is a coordinating conjunction and it cannot begin a sentence. One of the functions of a coordinating conjunction is to combine two independent clauses. The coordinating conjunction "but" joins the independent clause "Keira Knightley claims that she is not anorexic" and the independent clause "she explains that her grandmother and great-grandmother suffered from the eating disorder." The coordinating conjunction "so" does not join the independent clause "she knows it is a dangerous disease" to another independent clause.
One way to correct the error is to use the coordinating conjunction "so" to connect the independent clause that follows it to the sentence that precedes it.
Keira Knightley claims that she is not anorexic, but she explains that her grandmother and great-grandmother suffered from the eating disorder, so she knows it is a dangerous disease.
A more concise way to correct the error is to replace the coordinating conjunction with a conjunctive adverb, set off by a comma, that can introduce an independent clause.
Keira Knightley claims that she is not anorexic, but she explains that her grandmother and great-grandmother suffered from the eating disorder. Therefore, she knows it is a dangerous disease.
The conjunctive adverb "therefore" conveys the same meaning as the coordinating conjunction "so," and it is able to begin a sentence when it is set off by a comma. It would also be acceptable to use a semicolon after "disorder" and not capitalize "therefore" to separate the final independent clause from the rest of the sentence.
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